ENGLISH|院长信箱|书记信箱
师资队伍
孙桂鸿

1、职称职务: 副教授,博士生导师47孙桂鸿

2、学科专业: 病原微生物学

3、研究方向: 病毒感染免疫与肿瘤

4、联系电话: 13307180026

5、Email: ghsunlab@whu.edu.cn

6、学习经历:

  1994年获武汉大学理学学士学位,

  2006年获得武汉大学理学博士学位,

  2008.10-2010.9在美国国立卫生研究所做交流访问学者。

7、主要工作经历与任职 :

  1994-至今 武汉大学医学院

8、目前主要科学研究领域和兴趣:

  朊病毒的功能与致病机理,

  DNA、RNA病毒病毒感染免疫与肿瘤的关系。

9、教学情况:

  医学微生物学本科、7、8年制研究生教学,

  生物医学制药工程8年制教学,

  生物医学前言技术研究生教学

10、近5年代表性论文(近5年第一作者或通讯作者):

  1) Guihong Sun, Rachel A. Heimeier, Liezhen Fu, Takashi Hasebe, Biswajit Das,Atsuko Ishizuya-Oka, and Yun-Bo Shi. Expression profiling of intestinal tissues implicates tissue-specific genes and pathways essential for thyroid hormone-induced adult stem cell development. Endocrinology. 2013 Nov;154(11):4396-407.

  2) Thomas C. Miller, Guihong Sun, Takashi Hasebe, Liezhen Fu, Rachel A. Heimeier, Biswajit Das, Atsuko Ishizuya-Oka, Yun-Bo Shi. Tissue-Specific Upregulation of MDS/EVI Gene Transcripts in the Intestine by Thyroid Hormone during Xenopus Metamorphosis. PLoS One. 8(1):e55585, 2013.

  3) Guihong Sun*, Yun-Bo Shi*. Thyroid hormone regulation of adult intestinal stem cell development: mechanisms and evolutionary conservations. Int J Biol Sci. 8(8):1217-24, 2012.

  4) Fanghua Mei , Jin Xiang, Song Han, Yuan He, Yajing Lu, Jian Xu, Deyin Guo, Gengfu Xiao, Po Tien, Guihong Sun*.Expression, purification, and secondary structure characterization of recombinant KCTD1. Biochemistry (Mosc). 77(8):941-5, 2012.

  5) Liezhen Fu, Guihong Sun, Maria Fiorentino, Yun-Bo Shi. Characterization of Xenopus Tissue Inhibitor of Metalloproteinases-2: A role in regulating matrix metalloproteinase activity during development. PLoS One. 7(5):e36707, 2012.

  6) Tao Huang, Jian Xu, Jin Xiang, Yajing Lu, Rui Chen, Liqin Huang, Gengfu Xiao, Guihong Sun. PrPC interacts with potassium channel tetramerization domain containing 1 (KCTD1) protein through the PrP51-136 region containing octapeptide repeats. Biochem Biophys Res Commun. 2012 Jan 6;417(1):182-6

  7) Jin Xiang, Guihong Sun, Hui Liu, Yong-xin Mu, Ying Liu, Fang Yang, Jian Xu, and Hong Ding, Ritonavir stimulates foam cell formation by activating PKC, Chem. Bio. Interact. 2011, 194: 127-133.

  8) Guihong Sun, Takashi Hasebe, Kenta Fujimoto, Rosemary Lu, Liezhen Fu, Hiroki Matsuda, Mitsuko Kajita, Atsuko Ishizuya-Oka, Yun-Bo Shi. Spatio-temporal expression profile of stem cell-associated gene LGR5 in the intestine during thyroid hormone-dependent metamorphosis in Xenopus laevis. PLoS ONE. 2010 Oct 22;5(10):e13605.

  9) Guihong Sun, Biswajit Das, Liezhen Fu and Yun-Bo Shi. Temporal and Spatio-Regulation of Tissue-Specific Thyroid Hormone Response Genes during Intestinal Metamorphosis in Xenopus Laevis. Endocrine Reviews, Supplement 1, June 2010, 31[3]: S1477