Qin Pan, PH.D

E-mail Address: panqincn@whu.edu.cn

Office Address: Department of Immunology, Wuhan University School of Medicine, Donghu Road 185#, Wuhan, 430071, Hubei Province, P. R. China

Position(s): Associate Professor

Affiliation(s): Department of Immunology

Research interests / Specialties: Immunoregulation and Bacterial Pathogenesis

Education and Training

1996-2001, B.M. Wuhan University School of Medicine, Wuhan,

People’s Republic of China.

2001-2006, Ph.D. Wuhan University School of Medicine, Wuhan,

People’s Republic of China.

2010-2011 Visiting Researcher.University of Michigan, Medical school,USA

Research Description

We focused on Immunoregulation and infection immunology of intracellular pathogens.

Publication list

[1] Pan Q, Li Q, Liu S, Ning N, Zhang X, Xu Y, Chang AE, Wicha MS. Targeting Cancer Stem Cells Using Immunologic Approaches. Stem Cells. 2015 Apr 15. doi: 10.1002/stem.2039. [Epub ahead of print]

[2] Tao H, Lu L, Xia Y, Dai F, Wang Y, Bao Y, Lundy SK, Ito F, Pan Q, Zhang X, Zheng F, Shu G, Fang B, Jiang J, Xia J, Huang S, Li Q, Chang AE. Antitumor effector B cells directly kill tumor cells via tas/FasL pathway and are regulated by IL-10. Eur J Immunol. 2015;45(4):999-1009.

[3] Pan Q, Wang Q, Sun X, Xia X, Wu S, Luo F, Zhang XL.Aptamer against mannose-capped lipoarabinomannan inhibits virulent Mycobacterium tuberculosis infection in mice and rhesus monkeys. Mol Ther. 2014;22(5):940-51.

[4] Wu SM, Ai HW, Zhang DY, Han XQ, Pan Q, Luo FL, Zhang XL. miR-141 targets ZEB2 to suppress HCC progression. Tumour Biol. 2014;35(10):9993-7

[5] Tang XL, Zhou YX, Wu SM, Pan Q, Xia B, Zhang XL.CFP10 and ESAT6 aptamers as effective Mycobacterial antigen diagnostic reagents. J Infect. 2014;69(6):569-80.

[6] Liu M, Pan Q（co-first author）, Luo FL, Meyers C, Zhang XL*. Tumor carbohydrate antigens and strategies to develop cancer vaccines and drugs. Wuhan University Journal of Natural Sciences. 2013; 18: 1-8.

[7] Ning N, Pan Q(co-first author), Zheng F, Teitz-Tennenbaum S, Egenti M, Yet J, Li M, Ginestier C, Wicha M, Moyer J, Prince M, Xu Y, Zhang XL, Huang S, Chang A, Li Q*. Cancer stem cell vaccination confers significant anti-tumor immunity. Cancer Res. 2012 ; 72:1853-64

[8] Pan Q, Chen H, Wang F , Jeza VT , Hou W, Zhao Y, Xiang T, Zhu Y, Endo Y, Fujita T, Zhang XL*. L-ficolin binds to glycoproteins HA and NA and inhibits influenza A virus infection both in vitro and in vivo. J Innate Immun. 2012;4:312-24.

[9] Pan Q, Li Q*. New prospects for hepatocellular carcinoma therapy: microwave ablation working together with cellular immunotherapy. Cancer Biol Ther. 2011,11:642-3.

[10] Li G, Liu J, Pan Q(co-first author), Song Z, Luo F, Wang S, Zhang XL*, Zhou X . Synthesis and Anti-HIV Activity of [ddN]-[ddN] Dimers and Benzimidazole Nucleoside Dimers. Chem Biodivers. 2009, 6: 2200-8.

[11] Wang Q, Pan Q (co-first author), Ma Y, Wang K, Sun P, Liu S, Zhang XL*. An attenuated Salmonella-vectored vaccine elicits protective immunity against Mycobacterium tuberculosis. Vaccine. 2009; 27:6712-22.

[12] Pan Q, Zhang XL*, Wu HY, He PW, Wang F, Zhang MS, Hu JM, Xia B, Wu J. Identification of aptamers that preferentially bind the type IVB pili and inhibit human monocytic cell invasion by Salmonella enterica Serovar Typhi. Antimicrob Agents Chemother. 2005; 49:4052-60.

[13] Li Q, Lao X, Pan Q, Ning N, Yet J, Xu Y, Li S, Chang AE*. Adoptive transfer of tumor reactive B cells confers host T-cell immunity and tumor regression. Clin Cancer Res. 2011,17:4987-95.