Yun Chen, PH.D.
E-mail Address: yunchen@whu.edu.cn
Office Address: Building No.1, DongHu Road 185#, Wuhan, Hubei, 430071
Position: Professor
Affiliation: Department of Biomedical Engineering,
Research interests / Specialties: Biomedical Engineering/Biomaterials
Education and Training
B.S., 1987-1991, Southwest University, China
M.Sc., 1991-1994, Chemistry Research Institute of Hubei Province
Ph.D., 2001-2004, Wuhan University, China
Post-doctoral training, 2006-2008, Saskatoon Research Centre, Agriculture and Agri-Food Canada, Canada.
Research Description
The main research interests focus on biomaterials and regenerative medicine, including: (1) structure, properties, and modifications of the natural polymers such as cellulose, soy protein, chitosan, starch and their composites; (2) their interactions with tissues and biocompatibility evaluation; (3) and their applications in biomedical fields such as nerve tissue engineering, ligament nerve tissue engineering and bone nerve tissue engineering.
Publication list
1. Lihua Luo, Li Gan,, Yongming Liu, Weiqun Tian, Zan Tong, Xiong Wang , Celine Huselstein, Yun Chen*. Construction of nerve guide conduits fromcellulose/soy protein composite membranes combined with Schwann cells and pyrroloquinoline quinone for the repair of peripheral nerve defect. Biochem. Biophys. Res. 2015, 457, 507-513.
2. Xing Liu, Yi Xie, Wei Li, Wen Sheng, Yinping Li, Zan Tong, Hong Ni, Celine Huselstein, Xiong Wang, Yun Chen*. Structure, physical properties, hemocompatibility and cytocompatibility of starch/zein composites. Bio-med. Mater. Eng. 2015, 25, S47-S55.
3. Xinshen Du, Yinping Li, Xing Liu, Xiong Wang, Celine Huselstein, Yanteng Zhao, Peter R. Chang, Yun Chen*. Fabrication and evaluation of physical properties and cytotoxicity of zein-based polyurethanes. J. Mater. Sci.: Mater. Med. 2014, 25, 823-833.
4. Meng He, Yanteng Zhao, Jiangjiang Duan, Zhenggang Wang, Yun Chen, Lina Zhang*. Fast contact of solid−liquid interface created high strength multi-layered cellulose hydrogels with controllable size. ACS Appl. Mater. Interfaces 2014, 6, 1872-1878.
5. Meng He, Zhenggang Wang, Yan Cao, Yanteng Zhao, Bo Duan, Yun Chen, Min Xu, Lina Zhang*. Construction of chitin/pva composite hydrogels with jellyfish gel-like structure and their biocompatibility. Biomacromolecules 2014, 15, 3358-3365.
6. Xiaopeng Xiong*, Yong Wang, Weiwei Zou, Jiangjing Duan, Yun Chen*. Preparation and characterization of magnetic chitosan microcapsules. J. Chem. 2013, ID 585613, 8 pages.
7. Hong Ni, Siquan Zeng, Jing Wu, Xiangrong Cheng, Tao Luo, Weiyang Wang, Weijuan Zeng, Yun Chen*. Cellulose nanowhiskers: preparation, characterization and cytotoxicity evaluation. Bio-med. Mater. Eng. 2012, 22(1-3): 121-127.
8. Beibei Ding, Jie Cai, Junchao Huang, Lina Zhang, Yun Chen, Xiaowen Shi, Yumin Du, Shigenori Kugad. Facile preparation of robust and biocompatible chitin aerogels. J. Mater. Chem. 2012, 22, 5801-5809.
9. Xiaomei Wang, Peter R. Chang, Zonghuan Li, Hui Wang, Hui Liang, Xiaodong Cao*, Yun Chen*. Chitosan-coated cellulose/soy protein membranes with improved physical properties and hemocompatibility. Bioresources 2011, 6, 1392-1413.
10. Lihua Luo, Yufeng Zhang, Xiaomei Wang, Yu Wan, Peter R. Chang, Debbie P. Anderson, Yun Chen*. Preparation, characterization, and in vitro and in vivo evaluation of cellulose/soy protein isolate composite sponges. J. Biomater. Appl. 2010, 24, 503-526.
11. Chaoming Liu, Yun Chen*, Xiaomei Wang, Jin Huang, Peter R. Chang*, Debbie P. Anderson. Improvement in physical properties and cytocompatibility of zein by incorporation of pea protein isolate. J. Mater. Sci. 2010, 45, 6775–6785.
12. Huafeng Tian, Lina Zhang*, Qiangxian Wu, Xiaomei Wang, Yun Chen. Creation of hydrophobic materials fabricated from soy protein and natural rubber: surface, interface, and properties. Macromol. Mater. Eng. 2010, 295, 451–459.
13. Yun Chen, Changhua Liu, Debbie P. Anderson, Michel A. Huneault, Peter R. Chang*. Pea starch-based composite films with pea hull fibres and pea hull fibre-derived nanowhiskers. Polym. Eng. Sci. 2009, 49, 369-378.
14. Yun Chen, Changhua Liu, Peter R. Chang*, Xiaodong Cao, Debbie P. Anderson. Bionanocomposites based on pea starch and cellulose nanowhiskers hydrolyzed from pea hull fibre: effect of hydrolysis time. Carbohydr. Polym. 2009, 76, 607-615.
15. Yufeng Zhang, Bin Shi, Chengzhang Li, Yining Wang, Yun Chen, Wei Zhang, Tao Luo, Xiangrong Cheng*. The synergetic bone-forming effects of combinations of growth factors expressed by adenovirus vectors on chitosan/collagen scaffolds. J. Control. Releas. 2009, 136,172-178.
